DIAGNOSTIC AND TREATMENT CHALLENGES OF A CASE OF PRIMARY CUTANEOUS SIGNET-RING CELL/HISTIOCYTOID CARCINOMA OF THE EYELID

Diagnostic and treatment challenges of a case of primary cutaneous signet-ring cell/histiocytoid carcinoma of the eyelid

Abstract Background Primary cutaneous signet-ring cell/histiocytoid carcinoma of the eyelid is an extremely rare but aggressive neoplasm diagnosed primarily in elderly men.Until now there are 32 published cases of signet-ring cell carcinoma or histiocytoid carcinoma of the eyelid.We report the clinical, radiographic and histological features of the

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Long-term expansion of basal cells and the novel differentiation methods identify mechanisms for switching Claudin expression in normal epithelia

Abstract Epithelia are tightly connected cellular sheets, that shield our body from the external environment.They are continuously maintained by a pooled population of undifferentiated cells through differentiation.However, the maintenance mechanisms remain incompletely understood due to the difficulty of experimentally observing the differentiatio

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Analysis of metabolic differences between Jiaosu fermented from dendrobium flowers and stems based on untargeted metabolomics

Dendrobium officinale is an important traditional Chinese medicinal herb containing bioactive polysaccharides and alkaloids.This study characterized metabolite differences between jiaosu (fermented plant product) from Dendrobium flowers versus stems using untargeted metabolomics.The jiaosu was fermented by mixed fermentation of Saccharomyces cerevi

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